Hypoxia-Mediated ATF4 Induction Promotes Survival in Detached Conditions in Metastatic Murine Mammary Cancer Cells

Regions of hypoxia are common in solid tumors and drive changes in gene expression that increase risk of cancer metastasis. Tumor cells must respond to the stress of hypoxia by activating genes to modify cell metabolism and antioxidant response to improve survival. The goal of the current study was...

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Detalles Bibliográficos
Autores principales: Kiesel, Violet A., Sheeley, Madeline P., Hicks, Emily M., Andolino, Chaylen, Donkin, Shawn S., Wendt, Michael K., Hursting, Stephen D., Teegarden, Dorothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280133/
https://www.ncbi.nlm.nih.gov/pubmed/35847893
http://dx.doi.org/10.3389/fonc.2022.767479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280133/
https://www.ncbi.nlm.nih.gov/pubmed/35847893
http://dx.doi.org/10.3389/fonc.2022.767479

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