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Hypoxia-Mediated ATF4 Induction Promotes Survival in Detached Conditions in Metastatic Murine Mammary Cancer Cells
Regions of hypoxia are common in solid tumors and drive changes in gene expression that increase risk of cancer metastasis. Tumor cells must respond to the stress of hypoxia by activating genes to modify cell metabolism and antioxidant response to improve survival. The goal of the current study was...
Autores principales: | Kiesel, Violet A., Sheeley, Madeline P., Hicks, Emily M., Andolino, Chaylen, Donkin, Shawn S., Wendt, Michael K., Hursting, Stephen D., Teegarden, Dorothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280133/ https://www.ncbi.nlm.nih.gov/pubmed/35847893 http://dx.doi.org/10.3389/fonc.2022.767479 |
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