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IRSp53 promotes postsynaptic density formation and actin filament bundling

IRSp53 (aka BAIAP2) is a scaffold protein that couples membranes with the cytoskeleton in actin-filled protrusions such as filopodia and lamellipodia. The protein is abundantly expressed in excitatory synapses and is essential for synapse development and synaptic plasticity, although with poorly und...

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Detalles Bibliográficos
Autores principales: Feng, Zhe, Lee, Suho, Jia, Bowen, Jian, Tao, Kim, Eunjoon, Zhang, Mingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280192/
https://www.ncbi.nlm.nih.gov/pubmed/35819332
http://dx.doi.org/10.1083/jcb.202105035