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A novel 5-Fluorocuracil multiple-nanoemulsion used for the enhancement of oral bioavailability in the treatment of colorectal cancer

5-Fluorouracil (5-FU) is a drug of choice for colorectal-cancer. But oral therapeutic efficacy of 5-FU is restricted due to their very little bioavailability because of poor membrane permeability and GIT-absorption. We have developed a multiple nanoemulsion (w/o/w i.e. 5-FU-MNE) in which 5-FU incorp...

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Detalles Bibliográficos
Autores principales: Ahmad, Niyaz, Albassam, Ahmed A., Faiyaz Khan, Mohd, Ullah, Zabih, Mohammed Buheazah, Taysser, Salman AlHomoud, Hussain, Ali Al-Nasif, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280251/
https://www.ncbi.nlm.nih.gov/pubmed/35844373
http://dx.doi.org/10.1016/j.sjbs.2022.02.017