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Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing

In genes related to drug pharmacokinetics, molecular variations determine interindividual variability in the therapeutic efficacy and adverse drug reactions. The assessment of single-nucleotide variants (SNVs) is used with growing frequency in pharmacogenetic practice, and recently, high-throughput...

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Detalles Bibliográficos
Autores principales: Silgado-Guzmán, Daniel Felipe, Angulo-Aguado, Mariana, Morel, Adrien, Niño-Orrego, María José, Ruiz-Torres, Daniel-Armando, Contreras Bravo, Nora Constanza, Restrepo, Carlos Martin, Ortega-Recalde, Oscar, Fonseca-Mendoza, Dora Janeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280300/
https://www.ncbi.nlm.nih.gov/pubmed/35846994
http://dx.doi.org/10.3389/fphar.2022.931531