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Integration of Non-Targeted Metabolomics and Targeted Quantitative Analysis to Elucidate the Synergistic Antidepressant Effect of Bupleurum Chinense DC-Paeonia Lactiflora Pall Herb Pair by Regulating Purine Metabolism

Bupleurum chinense DC (Chaihu)-Paeonia lactiflora Pall (Baishao) is among the most accepted herb pairs in many classic antidepressant prescriptions. Our previous study has shown that the Chaihu–Baishao herb pair (CBHP) had a better antidepressant effect than Chaihu or Baishao. Nevertheless, the syne...

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Detalles Bibliográficos
Autores principales: Chen, Jiajun, Li, Tian, Qin, Xuemei, Du, Guanhua, Zhou, Yuzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280301/
https://www.ncbi.nlm.nih.gov/pubmed/35847012
http://dx.doi.org/10.3389/fphar.2022.900459