Turn-on fluorescent sensors for Cu-rich amyloid β peptide aggregates

Protein misfolding and metal dishomeostasis are two key pathological factors of Alzheimer's disease. Previous studies have shown that Cu-mediated amyloid β (Aβ) peptide aggregation leads to the formation of neurotoxic Aβ oligomers. Herein, we report a series of picolinic acid-based Cu-activatab...

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Detalles Bibliográficos
Autores principales: Huang, Yiran, Sun, Liang, Mirica, Liviu M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280444/
https://www.ncbi.nlm.nih.gov/pubmed/35923774
http://dx.doi.org/10.1039/d2sd00028h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280444/
https://www.ncbi.nlm.nih.gov/pubmed/35923774
http://dx.doi.org/10.1039/d2sd00028h

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