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Turn-on fluorescent sensors for Cu-rich amyloid β peptide aggregates
Protein misfolding and metal dishomeostasis are two key pathological factors of Alzheimer's disease. Previous studies have shown that Cu-mediated amyloid β (Aβ) peptide aggregation leads to the formation of neurotoxic Aβ oligomers. Herein, we report a series of picolinic acid-based Cu-activatab...
Autores principales: | Huang, Yiran, Sun, Liang, Mirica, Liviu M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280444/ https://www.ncbi.nlm.nih.gov/pubmed/35923774 http://dx.doi.org/10.1039/d2sd00028h |
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