A Novel Algorithm for Detecting Microsatellite Instability Based on Next-Generation Sequencing Data

OBJECTIVES: Microsatellite instability (MSI) is the condition of genetic hypermutability caused by spontaneous acquisition or loss of nucleotides during the DNA replication. MSI has been discovered to be a useful immunotherapy biomarker clinically. The main DNA-based method for MSI detection is poly...

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Detalles Bibliográficos
Autores principales: Li, Shijun, Wang, Bo, Chang, Miaomiao, Hou, Rui, Tian, Geng, Tong, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280483/
https://www.ncbi.nlm.nih.gov/pubmed/35847873
http://dx.doi.org/10.3389/fonc.2022.916379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280483/
https://www.ncbi.nlm.nih.gov/pubmed/35847873
http://dx.doi.org/10.3389/fonc.2022.916379

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