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Molecular basis of immunoglobulin heavy constant G4 gene (IGHG4)-related low serum IgG4 subclasses in Down syndrome

OBJECTIVES: To investigate the molecular mechanism of low serum IgG4 at the level of the immunoglobulin heavy constant G4 gene (IGHG4). Patients with Down syndrome (DS) are more likely to exhibit immunological abnormalities that predispose them to infection. Among other anomalies, individuals with D...

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Detalles Bibliográficos
Autor principal: Jeraiby, Mohammed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Saudi Medical Journal 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280510/
https://www.ncbi.nlm.nih.gov/pubmed/34470835
http://dx.doi.org/10.15537/smj.2021.42.9.20210030