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Molecular basis of immunoglobulin heavy constant G4 gene (IGHG4)-related low serum IgG4 subclasses in Down syndrome
OBJECTIVES: To investigate the molecular mechanism of low serum IgG4 at the level of the immunoglobulin heavy constant G4 gene (IGHG4). Patients with Down syndrome (DS) are more likely to exhibit immunological abnormalities that predispose them to infection. Among other anomalies, individuals with D...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Saudi Medical Journal
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280510/ https://www.ncbi.nlm.nih.gov/pubmed/34470835 http://dx.doi.org/10.15537/smj.2021.42.9.20210030 |