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Measuring Thousands of Single-Vesicle Leakage Events Reveals the Mode of Action of Antimicrobial Peptides

[Image: see text] Host defense or antimicrobial peptides hold promise for providing new pipelines of effective antimicrobial agents. Their activity quantified against model phospholipid membranes is fundamental to a detailed understanding of their structure–activity relationships. However, classical...

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Detalles Bibliográficos
Autores principales: Al Nahas, Kareem, Fletcher, Marcus, Hammond, Katharine, Nehls, Christian, Cama, Jehangir, Ryadnov, Maxim G., Keyser, Ulrich F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280716/
https://www.ncbi.nlm.nih.gov/pubmed/35760038
http://dx.doi.org/10.1021/acs.analchem.1c03564