Cargando…

Hypoxic Tumor-Derived Exosomes Induce M2 Macrophage Polarization via PKM2/AMPK to Promote Lung Cancer Progression

Hypoxia is a major regulator of tumor aggressiveness and metastasis in cancer progression. Exosomes (exos) play an important role in the communication between lung cancer and hypoxic microenvironment. However, the underlying mechanisms are largely undefined. Exos were isolated from A549 cells under...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Shiyu, Lan, Yu, Li, Yuqun, Li, Zhenxing, Pu, Jinding, Wei, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280815/
https://www.ncbi.nlm.nih.gov/pubmed/35818293
http://dx.doi.org/10.1177/09636897221106998