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Metabolomics and Data-Driven Bioinformatics Revealed Key Maternal Metabolites Related to Fetal Lethality via Di(2-ethylhexyl)phthalate Exposure in Pregnant Mice

[Image: see text] We performed serum metabolome analysis of di(2-ethylhexyl)phthalate (DEHP)-exposed and control pregnant mice. Pregnant mice (n = 5) were fed a DEHP-containing diet (0.1% or 0.2% DEHP) or a normal diet (control) from gestational days 0–18. After maternal exposure to 0.2% DEHP there...

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Detalles Bibliográficos
Autores principales: Zaitsu, Kei, Asano, Tomomi, Kawakami, Daisuke, Chang, Jiarui, Hisatsune, Kazuaki, Taniguchi, Masaru, Iguchi, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280929/
https://www.ncbi.nlm.nih.gov/pubmed/35847272
http://dx.doi.org/10.1021/acsomega.2c02338