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Ion-Dependent Conformational Plasticity of Telomeric G-Hairpins and G-Quadruplexes
[Image: see text] Telomeric DNA is guanine-rich and can adopt structures such as G-quadruplexes (GQs) and G-hairpins. Telomeric GQs influence genome stability and telomerase activity, making understanding of enzyme–GQ interactions and dynamics important for potential drug design. GQs have a characte...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280957/ https://www.ncbi.nlm.nih.gov/pubmed/35847338 http://dx.doi.org/10.1021/acsomega.2c01600 |