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Ion-Dependent Conformational Plasticity of Telomeric G-Hairpins and G-Quadruplexes

[Image: see text] Telomeric DNA is guanine-rich and can adopt structures such as G-quadruplexes (GQs) and G-hairpins. Telomeric GQs influence genome stability and telomerase activity, making understanding of enzyme–GQ interactions and dynamics important for potential drug design. GQs have a characte...

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Detalles Bibliográficos
Autores principales: Salsbury, Alexa M., Michel, Haley M., Lemkul, Justin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280957/
https://www.ncbi.nlm.nih.gov/pubmed/35847338
http://dx.doi.org/10.1021/acsomega.2c01600