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Immune-regulating strategy against rheumatoid arthritis by inducing tolerogenic dendritic cells with modified zinc peroxide nanoparticles

In hypoxic dendritic cells (DCs), a low level of Zn(2+) can induce the activation of immunogenic DCs (igDCs), thereby triggering an active T-cell response to propel the immune progression of rheumatoid arthritis (RA). This finding indicates the crucial roles of zinc and oxygen homeostasis in DCs dur...

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Detalles Bibliográficos
Autores principales: Qiao, Han, Mei, Jingtian, Yuan, Kai, Zhang, Kai, Zhou, Feng, Tang, Tingting, Zhao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281050/
https://www.ncbi.nlm.nih.gov/pubmed/35836178
http://dx.doi.org/10.1186/s12951-022-01536-0