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Arecoline promotes proliferation and migration of human HepG2 cells through activation of the PI3K/AKT/mTOR pathway

BACKGROUND: Arecoline is a well-known risk factor for oral submucosal fibrosis and cancer. However, the mechanistic correlation between arecoline and hepatocellular cancer remains elusive. Here, we investigated the effect of arecoline on the proliferation and migration of human HepG2 hepatoma cells...

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Detalles Bibliográficos
Autores principales: Xie, Hai, Jing, Ren, Liao, Xiaoting, Chen, Haishao, Xie, Xianlong, Dai, Huijun, Pan, Linghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281068/
https://www.ncbi.nlm.nih.gov/pubmed/35836300
http://dx.doi.org/10.1186/s41065-022-00241-0