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Huc-MSCs-derived exosomes attenuate inflammatory pain by regulating microglia pyroptosis and autophagy via the miR-146a-5p/TRAF6 axis

BACKGROUND: Chronic inflammatory pain significantly reduces the quality of life and lacks effective interventions. In recent years, human umbilical cord mesenchymal stem cells (huc-MSCs)-derived exosomes have been used to relieve neuropathic pain and other inflammatory diseases as a promising cell-f...

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Detalles Bibliográficos
Autores principales: Hua, Tong, Yang, Mei, Song, Honghao, Kong, Erliang, Deng, Mengqiu, Li, Yongchang, Li, Jian, Liu, Zhixiao, Fu, Hailong, Wang, Yue, Yuan, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281091/
https://www.ncbi.nlm.nih.gov/pubmed/35836229
http://dx.doi.org/10.1186/s12951-022-01522-6