Cargando…

Anesthetic propofol enhances cisplatin-sensitivity of non-small cell lung cancer cells through N6-methyladenosine-dependently regulating the miR-486-5p/RAP1-NF-κB axis

BACKGROUND: Drug resistance is a considerable challenge for chemotherapy in non-small cell lung cancer (NSCLC). Propofol, a commonly used intravenous anesthetics, has been reported to suppress the malignancy of various cancers. However, the effects of propofol on cisplatin (DDP) sensitivity in NSCLC...

Descripción completa

Detalles Bibliográficos
Autores principales: Ling, Quan, Wu, Shaoyong, Liao, Xiaozu, Liu, Chiyi, Chen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281112/
https://www.ncbi.nlm.nih.gov/pubmed/35836137
http://dx.doi.org/10.1186/s12885-022-09848-y