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Anesthetic propofol enhances cisplatin-sensitivity of non-small cell lung cancer cells through N6-methyladenosine-dependently regulating the miR-486-5p/RAP1-NF-κB axis

BACKGROUND: Drug resistance is a considerable challenge for chemotherapy in non-small cell lung cancer (NSCLC). Propofol, a commonly used intravenous anesthetics, has been reported to suppress the malignancy of various cancers. However, the effects of propofol on cisplatin (DDP) sensitivity in NSCLC...

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Detalles Bibliográficos
Autores principales:	Ling, Quan, Wu, Shaoyong, Liao, Xiaozu, Liu, Chiyi, Chen, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281112/ https://www.ncbi.nlm.nih.gov/pubmed/35836137 http://dx.doi.org/10.1186/s12885-022-09848-y

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