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Highly sensitive Curcumin-conjugated nanotheranostic platform for detecting amyloid-beta plaques by magnetic resonance imaging and reversing cognitive deficits of Alzheimer's disease via NLRP3-inhibition

BACKGROUND: Alzheimer's disease (AD) is the most common neurodegenerative disorder without effective therapy and lack diagnosis strategy for preclinical AD patients. There is an urgent need for development of both early diagnosis and therapeutic intervention of AD. RESULTS: Herein, we developed...

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Detalles Bibliográficos
Autores principales: Ruan, Yuting, Xiong, Ying, Fang, Wenli, Yu, Qun, Mai, Yingren, Cao, Zhiyu, Wang, Kexi, Lei, Ming, Xu, Jiaxin, Liu, Yan, Zhang, Xingcai, Liao, Wang, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281113/
https://www.ncbi.nlm.nih.gov/pubmed/35836190
http://dx.doi.org/10.1186/s12951-022-01524-4