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Highly sensitive Curcumin-conjugated nanotheranostic platform for detecting amyloid-beta plaques by magnetic resonance imaging and reversing cognitive deficits of Alzheimer's disease via NLRP3-inhibition
BACKGROUND: Alzheimer's disease (AD) is the most common neurodegenerative disorder without effective therapy and lack diagnosis strategy for preclinical AD patients. There is an urgent need for development of both early diagnosis and therapeutic intervention of AD. RESULTS: Herein, we developed...
Autores principales: | Ruan, Yuting, Xiong, Ying, Fang, Wenli, Yu, Qun, Mai, Yingren, Cao, Zhiyu, Wang, Kexi, Lei, Ming, Xu, Jiaxin, Liu, Yan, Zhang, Xingcai, Liao, Wang, Liu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281113/ https://www.ncbi.nlm.nih.gov/pubmed/35836190 http://dx.doi.org/10.1186/s12951-022-01524-4 |
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