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DriverRWH: discovering cancer driver genes by random walk on a gene mutation hypergraph

BACKGROUND: Recent advances in next-generation sequencing technologies have helped investigators generate massive amounts of cancer genomic data. A critical challenge in cancer genomics is identification of a few cancer driver genes whose mutations cause tumor growth. However, the majority of existi...

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Detalles Bibliográficos
Autores principales: Wang, Chenye, Shi, Junhan, Cai, Jiansheng, Zhang, Yusen, Zheng, Xiaoqi, Zhang, Naiqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281118/
https://www.ncbi.nlm.nih.gov/pubmed/35831792
http://dx.doi.org/10.1186/s12859-022-04788-7