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ZG16 promotes T-cell mediated immunity through direct binding to PD-L1 in colon cancer

Immunotherapy using programmed cell death 1 (PD1) inhibitors has shown great efficacy in colorectal cancer patients harboring mismatch-repair-deficient (dMMR) and microsatellite instability-high (MSI-H) alterations. We previously showed a negative correlation of zymogen granule protein 16 (ZG16) wit...

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Detalles Bibliográficos
Autores principales: Meng, Hui, Yao, Wu, Yin, Yuhui, Li, Yizhen, Ding, Yi, Wang, Liang, Zhang, Mingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281127/
https://www.ncbi.nlm.nih.gov/pubmed/35831911
http://dx.doi.org/10.1186/s40364-022-00396-y