Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor

BACKGROUND: Perioperative neurocognitive disorders (PNDs) are considered the most common postoperative complication in geriatric patients. However, its pathogenesis is not fully understood. Surgery-triggered neuroinflammation is a major contributor to the development of PNDs. Neuroinflammation can i...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Bo, Qin, Guangcheng, Xiao, Jingyu, Deng, Xiaoyuan, Lin, Aolei, Liu, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281167/
https://www.ncbi.nlm.nih.gov/pubmed/35831873
http://dx.doi.org/10.1186/s12974-022-02528-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281167/
https://www.ncbi.nlm.nih.gov/pubmed/35831873
http://dx.doi.org/10.1186/s12974-022-02528-5

Ejemplares similares