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Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor

BACKGROUND: Perioperative neurocognitive disorders (PNDs) are considered the most common postoperative complication in geriatric patients. However, its pathogenesis is not fully understood. Surgery-triggered neuroinflammation is a major contributor to the development of PNDs. Neuroinflammation can i...

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Detalles Bibliográficos
Autores principales:	Chen, Bo, Qin, Guangcheng, Xiao, Jingyu, Deng, Xiaoyuan, Lin, Aolei, Liu, Hongliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281167/ https://www.ncbi.nlm.nih.gov/pubmed/35831873 http://dx.doi.org/10.1186/s12974-022-02528-5

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