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GABRP promotes CD44s-mediated gemcitabine resistance in pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) has the worst five-year overall survival rate among all cancer types. Acquired chemoresistance is considered one of the main reasons for this dismal prognosis, and the mechanism of chemoresistance is unknown. METHODS: We previously identified a sub...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Wu, Binfeng, Wang, Mingge, Chen, Jinghua, Huang, Zhaohui, Shi, Jin-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281597/
https://www.ncbi.nlm.nih.gov/pubmed/35846884
http://dx.doi.org/10.7717/peerj.12728