Cargando…

GABRP promotes CD44s-mediated gemcitabine resistance in pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) has the worst five-year overall survival rate among all cancer types. Acquired chemoresistance is considered one of the main reasons for this dismal prognosis, and the mechanism of chemoresistance is unknown. METHODS: We previously identified a sub...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Chen, Wu, Binfeng, Wang, Mingge, Chen, Jinghua, Huang, Zhaohui, Shi, Jin-Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281597/ https://www.ncbi.nlm.nih.gov/pubmed/35846884 http://dx.doi.org/10.7717/peerj.12728

Ejemplares similares

The Association of the GABRP Polymorphisms with Systemic Lupus Erythematosus
por: Kim, Hun-Soo, et al.
Publicado: (2015)

Gemcitabine resistance of pancreatic cancer cells is mediated by IGF1R dependent upregulation of CD44 expression and isoform switching
por: Chen, Chen, et al.
Publicado: (2022)

Elevated GABRP expression is correlated to the excessive autophagy in intrahepatic cholestasis of pregnancy
por: Dong, Ruihong, et al.
Publicado: (2023)

GABRP is a potential prognostic biomarker and correlated with immune infiltration and tumor microenvironment in pancreatic cancer
por: Yang, Yihui, et al.
Publicado: (2022)

Inhibition of Gabrp reduces the differentiation of airway epithelial progenitor cells into goblet cells
por: Wang, An, et al.
Publicado: (2021)

Aberrant epigenetic regulation of GABRP associates with aggressive phenotype of ovarian cancer
por: Sung, Hye Youn, et al.
Publicado: (2017)

The role of m6A-related genes in the prognosis and immune microenvironment of pancreatic adenocarcinoma
por: Tang, Rong, et al.
Publicado: (2020)

Abnormal expression of HOXD11 promotes the malignant behavior of glioma cells and leads to poor prognosis of glioma patients
por: Wang, Jialin, et al.
Publicado: (2021)

Dipeptidyl peptidase like 6 promoter methylation is a potential prognostic biomarker for pancreatic ductal adenocarcinoma
por: Zhao, Xin, et al.
Publicado: (2020)

Identify potential prognostic indicators and tumor-infiltrating immune cells in pancreatic adenocarcinoma
por: Shi, Ting, et al.
Publicado: (2022)

Comparative chloroplast genome analyses of diverse Phoebe (Lauraceae) species endemic to China provide insight into their phylogeographical origin
por: Shi, Wenbo, et al.
Publicado: (2023)

Gene signature for prognosis in comparison of pancreatic cancer patients with diabetes and non-diabetes
por: Yang, Mingjun, et al.
Publicado: (2020)

Identification of prognostic splicing factors and exploration of their potential regulatory mechanisms in pancreatic adenocarcinoma
por: Rong, Min-hua, et al.
Publicado: (2020)

RNA sequencing of CD4 T-cells reveals the relationships between lncRNA-mRNA co-expression in elite controller vs. HIV-positive infected patients
por: Chen, Chaoyu, et al.
Publicado: (2020)

Identification of prognostic risk factors for pancreatic cancer using bioinformatics analysis
por: Jin, Dandan, et al.
Publicado: (2020)

The nine ADAMs family members serve as potential biomarkers for immune infiltration in pancreatic adenocarcinoma
por: Qi, Bing, et al.
Publicado: (2020)

CD37 high expression as a potential biomarker and association with poor outcome in acute myeloid leukemia
por: Zhang, Qi, et al.
Publicado: (2020)

Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments
por: Lei, Xiaohua, et al.
Publicado: (2021)

Characterization of the salivary microbiome in patients with pancreatic cancer
por: Torres, Pedro J., et al.
Publicado: (2015)

Mechanism of BIP-4 mediated inhibition of InsP(3)Kinase-A
por: Paraschiakos, Themistoklis, et al.
Publicado: (2021)

Expression and promoter analysis of MEP pathway enzyme-encoding genes in Pinus massoniana Lamb
por: Zhu, Peihuang, et al.
Publicado: (2022)

METTL3-mediated m6A modification of has_circ_0007905 promotes age-related cataract progression through miR-6749-3p/EIF4EBP1
por: Li, Rui, et al.
Publicado: (2023)

Pan‐cancer analyses reveal that increased Hedgehog activity correlates with tumor immunosuppression and resistance to immune checkpoint inhibitors
por: Jiang, Junjie, et al.
Publicado: (2021)

GABRP is a Promising Prognostic Biomarker and Associated with Immune Cell Infiltration in Lung Squamous Cell Carcinoma
por: Fu, Jiding, et al.
Publicado: (2023)

Ferroptosis: At the Crossroad of Gemcitabine Resistance and Tumorigenesis in Pancreatic Cancer
por: Yang, Jianhui, et al.
Publicado: (2021)

The role of phosphoprotein phosphatases catalytic subunit genes in pancreatic cancer
por: Hang, Junjie, et al.
Publicado: (2021)

GBP2 as a potential prognostic biomarker in pancreatic adenocarcinoma
por: Liu, Bo, et al.
Publicado: (2021)

Cell division cycle associated 2 (CDCA2) upregulation promotes the progression of hepatocellular carcinoma in a p53-dependant manner
por: Wang, Jiahui, et al.
Publicado: (2022)

Estrogen receptor—positive breast cancer survival prediction and analysis of resistance–related genes introduction
por: Shuai, Chen, et al.
Publicado: (2021)

METTL16-mediated translation of CIDEA promotes non-alcoholic fatty liver disease progression via m6A-dependent manner
por: Tang, Jinhong, et al.
Publicado: (2022)

High expression of MAPK-14 promoting the death of chondrocytes is an important signal of osteoarthritis process
por: Deng, Zhiqin, et al.
Publicado: (2021)

CD44V3, an Alternatively Spliced Form of CD44, Promotes Pancreatic Cancer Progression
por: Zhu, Hanzhang, et al.
Publicado: (2022)

CNV-P: a machine-learning framework for predicting high confident copy number variations
por: Wang, Taifu, et al.
Publicado: (2021)

Expression and correlation of COX-2 and NUCB1 in colorectal adenocarcinoma
por: Zhang, Yuanyuan, et al.
Publicado: (2023)

In silico approach to predict pancreatic β-cells classically secreted proteins
por: Pinheiro-Machado, Erika, et al.
Publicado: (2020)

IQGAP3 in clear cell renal cell carcinoma contributes to drug resistance and genome stability
por: Li, Wen, et al.
Publicado: (2022)

TTC13 expression and STAT3 activation may form a positive feedback loop to promote ccRCC progression
por: Xie, Lingling, et al.
Publicado: (2023)

KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas
por: Wang, Dan, et al.
Publicado: (2023)

LINC00106/RPS19BP1/p53 axis promotes the proliferation and migration of human prostate cancer cells
por: Lu, Lingxiang, et al.
Publicado: (2023)

Sterol regulatory element binding transcription factor 1 promotes proliferation and migration in head and neck squamous cell carcinoma
por: Tan, Ming, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lg9cvgvjo7ise4dc5km26gpj13