Cargando…

Beyond GalNAc! Drug delivery systems comprising complex oligosaccharides for targeted use of nucleic acid therapeutics

Nucleic Acid Therapeutics (NATs) are establishing a leading role for the management and treatment of genetic diseases following FDA approval of nusinersen, patisiran, and givosiran in the last 5 years, the breakthrough of milasen, with more approvals undoubtedly on the way. Givosiran takes advantage...

Descripción completa

Detalles Bibliográficos
Autores principales: O'Sullivan, Joseph, Muñoz-Muñoz, Jose, Turnbull, Graeme, Sim, Neil, Penny, Stuart, Moschos, Sterghios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281799/
https://www.ncbi.nlm.nih.gov/pubmed/35919168
http://dx.doi.org/10.1039/d2ra01999j