Cargando…

PLK1 depletion alters homologous recombination and synaptonemal complex disassembly events during mammalian spermatogenesis

Homologous recombination (HR) is an essential meiotic process that contributes to the genetic variation of offspring and ensures accurate chromosome segregation. Recombination is facilitated by the formation and repair of programmed DNA double-strand breaks. These DNA breaks are repaired via recombi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wellard, Stephen R., Skinner, Marnie W., Zhao, Xueqi, Shults, Chris, Jordan, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282006/
https://www.ncbi.nlm.nih.gov/pubmed/35274968
http://dx.doi.org/10.1091/mbc.E21-03-0115