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Centrosomal enrichment and proteasomal degradation of SYS-1/β-catenin requires the microtubule motor dynein

The Caenorhabditis elegans Wnt/β-catenin asymmetry (WβA) pathway utilizes asymmetric regulation of SYS-1/β-catenin and POP-1/TCF coactivators. WβA differentially regulates gene expression during cell fate decisions, specifically by asymmetric localization of determinants in mother cells to produce d...

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Detalles Bibliográficos
Autores principales: Thompson, Joshua W., Michel, Maria F. Valdes, Phillips, Bryan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282011/
https://www.ncbi.nlm.nih.gov/pubmed/35196020
http://dx.doi.org/10.1091/mbc.E22-02-0031