Cargando…

A perinuclear α-helix with amphipathic features in Brl1 promotes NPC assembly

How nuclear pore complexes (NPCs) assemble in the intact nuclear envelope (NE) is only rudimentarily understood. Nucleoporins (Nups) accumulate at the inner nuclear membrane (INM) and deform this membrane toward the outer nuclear membrane (ONM), and eventually INM and ONM fuse by an unclear mechanis...

Descripción completa

Detalles Bibliográficos
Autores principales: Vitale, Jlenia, Khan, Azqa, Neuner, Annett, Schiebel, Elmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282021/
https://www.ncbi.nlm.nih.gov/pubmed/35293775
http://dx.doi.org/10.1091/mbc.E21-12-0616