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Characterization of a thermostable Cas13 enzyme for one-pot detection of SARS-CoV-2

Type VI CRISPR-Cas systems have been repurposed for various applications such as gene knockdown, viral interference, and diagnostics. However, the identification and characterization of thermophilic orthologs will expand and unlock the potential of diverse biotechnological applications. Herein, we i...

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Detalles Bibliográficos
Autores principales: Mahas, Ahmed, Marsic, Tin, Lopez-Portillo Masson, Mauricio, Wang, Qiaochu, Aman, Rashid, Zheng, Cheng, Ali, Zahir, Alsanea, Madain, Al-Qahtani, Ahmed, Ghanem, Bernard, Alhamlan, Fatimah, Mahfouz, Magdy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282225/
https://www.ncbi.nlm.nih.gov/pubmed/35763567
http://dx.doi.org/10.1073/pnas.2118260119