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Kisspeptin Overcomes GnRH Neuronal Suppression Secondary to Hyperprolactinemia in Humans

CONTEXT: Hyperprolactinemia suppresses gonadotropin-releasing hormone (GnRH)-induced luteinizing hormone (LH) pulses. The hypothalamic neuropeptide kisspeptin potently stimulates the secretion of GnRH. The effects of exogenous kisspeptin administration on GnRH pulse generation in the setting of hype...

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Detalles Bibliográficos
Autores principales: Hoskova, Katerina, Kayton Bryant, Nora, Chen, Margaret E, Nachtigall, Lisa B, Lippincott, Margaret F, Balasubramanian, Ravikumar, Seminara, Stephanie B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282259/
https://www.ncbi.nlm.nih.gov/pubmed/35323937
http://dx.doi.org/10.1210/clinem/dgac166