A conserved signal-peptidase antagonist modulates membrane homeostasis of actinobacterial sortase critical for surface morphogenesis

Most Actinobacteria encode a small transmembrane protein, whose gene lies immediately downstream of the housekeeping sortase coding for a transpeptidase that anchors many extracellular proteins to the Gram-positive bacterial cell wall. Here, we uncover the hitherto unknown function of this class of...

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Detalles Bibliográficos
Autores principales: Ramirez, Nicholas A., Wu, Chenggang, Chang, Chungyu, Siegel, Sara D., Das, Asis, Ton-That, Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282373/
https://www.ncbi.nlm.nih.gov/pubmed/35787040
http://dx.doi.org/10.1073/pnas.2203114119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282373/
https://www.ncbi.nlm.nih.gov/pubmed/35787040
http://dx.doi.org/10.1073/pnas.2203114119

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