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Antiprion systems in yeast cooperate to cure or prevent the generation of nearly all [PSI(+)] and [URE3] prions
[PSI(+)] and [URE3] are prions of Saccharomyces cerevisiae based on amyloids of Sup35p and Ure2p, respectively. In normal cells, antiprion systems block prion formation, cure many prions that arise, prevent infection by prions, and prevent toxicity of those prions that escape the other systems. The...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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National Academy of Sciences
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282430/ https://www.ncbi.nlm.nih.gov/pubmed/35787049 http://dx.doi.org/10.1073/pnas.2205500119 |