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Antiprion systems in yeast cooperate to cure or prevent the generation of nearly all [PSI(+)] and [URE3] prions

[PSI(+)] and [URE3] are prions of Saccharomyces cerevisiae based on amyloids of Sup35p and Ure2p, respectively. In normal cells, antiprion systems block prion formation, cure many prions that arise, prevent infection by prions, and prevent toxicity of those prions that escape the other systems. The...

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Detalles Bibliográficos
Autores principales: Son, Moonil, Wickner, Reed B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282430/
https://www.ncbi.nlm.nih.gov/pubmed/35787049
http://dx.doi.org/10.1073/pnas.2205500119