Optimization and evaluation of a two-stage chromogenic assay procedure for measurement of emicizumab plasma levels

Emicizumab mimics the hemostatic activity of activated factor VIII (FVIIIa) within the tenase complex. Despite functional similarities between FVIIIa and emicizumab, conventional laboratory methods designed for monitoring of FVIII activity are inappropriate for the measurement of emicizumab. At pres...

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Detalles Bibliográficos
Autores principales: Hamedani, Nasim Shahidi, Oldenburg, Johannes, Pötzsch, Bernd, Müller, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282532/
https://www.ncbi.nlm.nih.gov/pubmed/35834493
http://dx.doi.org/10.1371/journal.pone.0271330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282532/
https://www.ncbi.nlm.nih.gov/pubmed/35834493
http://dx.doi.org/10.1371/journal.pone.0271330

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