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Optimization and evaluation of a two-stage chromogenic assay procedure for measurement of emicizumab plasma levels
Emicizumab mimics the hemostatic activity of activated factor VIII (FVIIIa) within the tenase complex. Despite functional similarities between FVIIIa and emicizumab, conventional laboratory methods designed for monitoring of FVIII activity are inappropriate for the measurement of emicizumab. At pres...
Autores principales: | Hamedani, Nasim Shahidi, Oldenburg, Johannes, Pötzsch, Bernd, Müller, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282532/ https://www.ncbi.nlm.nih.gov/pubmed/35834493 http://dx.doi.org/10.1371/journal.pone.0271330 |
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