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Association between urinary biomarkers MMP-7/TIMP-2 and reduced renal function in children with ureteropelvic junction obstruction

IMPORTANCE: Extracellular matrix proteins and enzymes involved in degradation have been found to be associated with tissue fibrosis and ureteropelvic junction obstruction (UPJO). In this study we developed a promising urinary biomarker model which can identify reduced renal function in UPJ obstructi...

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Detalles Bibliográficos
Autores principales: Wang, Hsin-Hsiao S., Cho, Patricia S., Zhi, Hui, Kostel, Stephen A., DiMartino, Shannon, Dagher, Adelle M., Davis, Kylie H., Cabour, Lily D., Shimmel, Ashley, Lee, James, Froehlich, John W., Zurakowski, David, Moses, Marsha A., Lee, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282603/
https://www.ncbi.nlm.nih.gov/pubmed/35834547
http://dx.doi.org/10.1371/journal.pone.0270018