Structure-Based Prediction of hERG-Related Cardiotoxicity: A Benchmark Study

[Image: see text] Drug-induced blockade of the human ether-à-go-go-related gene (hERG) channel is today considered the main cause of cardiotoxicity in postmarketing surveillance. Hence, several ligand-based approaches were developed in the last years and are currently employed in the early stages of...

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Detalles Bibliográficos
Autores principales: Creanza, Teresa Maria, Delre, Pietro, Ancona, Nicola, Lentini, Giovanni, Saviano, Michele, Mangiatordi, Giuseppe Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282647/
https://www.ncbi.nlm.nih.gov/pubmed/34506150
http://dx.doi.org/10.1021/acs.jcim.1c00744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282647/
https://www.ncbi.nlm.nih.gov/pubmed/34506150
http://dx.doi.org/10.1021/acs.jcim.1c00744

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