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Structure-Based Prediction of hERG-Related Cardiotoxicity: A Benchmark Study
[Image: see text] Drug-induced blockade of the human ether-à-go-go-related gene (hERG) channel is today considered the main cause of cardiotoxicity in postmarketing surveillance. Hence, several ligand-based approaches were developed in the last years and are currently employed in the early stages of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282647/ https://www.ncbi.nlm.nih.gov/pubmed/34506150 http://dx.doi.org/10.1021/acs.jcim.1c00744 |