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Poxviruses package viral redox proteins in lateral bodies and modulate the host oxidative response

All poxviruses contain a set of proteinaceous structures termed lateral bodies (LB) that deliver viral effector proteins into the host cytosol during virus entry. To date, the spatial proteotype of LBs remains unknown. Using the prototypic poxvirus, vaccinia virus (VACV), we employed a quantitative...

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Detalles Bibliográficos
Autores principales: Bidgood, Susanna R., Samolej, Jerzy, Novy, Karel, Collopy, Abigail, Albrecht, David, Krause, Melanie, Burden, Jemima J., Wollscheid, Bernd, Mercer, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282662/
https://www.ncbi.nlm.nih.gov/pubmed/35834477
http://dx.doi.org/10.1371/journal.ppat.1010614