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Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma

Prostaglandin E(2) (PGE(2)) promotes tumor cell proliferation, migration, and invasion, fostering an inflammation-enriched microenvironment that facilitates angiogenesis and immune evasion. However, the PGE(2) receptor subtype (EP1–EP4) involved in neuroblastoma (NB) growth remains elusive. Herein,...

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Detalles Bibliográficos
Autores principales: Hou, Ruida, Yu, Ying, Sluter, Madison N., Li, Lexiao, Hao, Jiukuan, Fang, Jie, Yang, Jun, Jiang, Jianxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282716/
https://www.ncbi.nlm.nih.gov/pubmed/35732130
http://dx.doi.org/10.1016/j.celrep.2022.111000