Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway

OBJECTIVE(S): Excess intake of a high-fatty diet (HFD) together with zymosan administration mediates vasculitis response which leads to impaired serum lipid levels and causes arterial stiffness. In the development of new cholesterol-lowering medications, PCSK9 inhibitor (proprotein convertase subtil...

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Detalles Bibliográficos
Autores principales: Arya, Priyanka, Bhandari, Uma, Sharma, Kalicharan, Bansal, Priyanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282737/
https://www.ncbi.nlm.nih.gov/pubmed/35911646
http://dx.doi.org/10.22038/IJBMS.2022.60467.13404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282737/
https://www.ncbi.nlm.nih.gov/pubmed/35911646
http://dx.doi.org/10.22038/IJBMS.2022.60467.13404

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