Cargando…

MAPK15 protects from oxidative stress‐dependent cellular senescence by inducing the mitophagic process

Mitochondria are the major source of reactive oxygen species (ROS), whose aberrant production by dysfunctional mitochondria leads to oxidative stress, thus contributing to aging as well as neurodegenerative disorders and cancer. Cells efficiently eliminate damaged mitochondria through a selective ty...

Descripción completa

Detalles Bibliográficos
Autores principales: Franci, Lorenzo, Tubita, Alessandro, Bertolino, Franca Maria, Palma, Alessandro, Cannino, Giuseppe, Settembre, Carmine, Rasola, Andrea, Rovida, Elisabetta, Chiariello, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282834/
https://www.ncbi.nlm.nih.gov/pubmed/35642724
http://dx.doi.org/10.1111/acel.13620