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A rare natural lipid induces neuroglobin expression to prevent amyloid oligomers toxicity and retinal neurodegeneration

Most neurodegenerative diseases such as Alzheimer's disease are proteinopathies linked to the toxicity of amyloid oligomers. Treatments to delay or cure these diseases are lacking. Using budding yeast, we report that the natural lipid tripentadecanoin induces expression of the nitric oxide oxid...

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Detalles Bibliográficos
Autores principales: Oamen, Henry Patrick, Romero Romero, Nathaly, Knuckles, Philip, Saarikangas, Juha, Radman‐Livaja, Marta, Dong, Yuhong, Caudron, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282837/
https://www.ncbi.nlm.nih.gov/pubmed/35656861
http://dx.doi.org/10.1111/acel.13645