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Lifelong cytomegalovirus and early‐LIFE irradiation synergistically potentiate age‐related defects in response to vaccination and infection

While whole‐body irradiation (WBI) can induce some hallmarks of immune aging, (re)activation of persistent microbial infection also occurs following WBI and may contribute to immune effects of WBI over the lifespan. To test this hypothesis in a model relevant to human immune aging, we examined separ...

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Detalles Bibliográficos
Autores principales: Pugh, Jason L., Coplen, Christopher P., Sukhina, Alona S., Uhrlaub, Jennifer L., Padilla‐Torres, Jose, Hayashi, Tomonori, Nikolich‐Žugich, Janko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282846/
https://www.ncbi.nlm.nih.gov/pubmed/35657768
http://dx.doi.org/10.1111/acel.13648