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Lifelong cytomegalovirus and early‐LIFE irradiation synergistically potentiate age‐related defects in response to vaccination and infection
While whole‐body irradiation (WBI) can induce some hallmarks of immune aging, (re)activation of persistent microbial infection also occurs following WBI and may contribute to immune effects of WBI over the lifespan. To test this hypothesis in a model relevant to human immune aging, we examined separ...
Autores principales: | Pugh, Jason L., Coplen, Christopher P., Sukhina, Alona S., Uhrlaub, Jennifer L., Padilla‐Torres, Jose, Hayashi, Tomonori, Nikolich‐Žugich, Janko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282846/ https://www.ncbi.nlm.nih.gov/pubmed/35657768 http://dx.doi.org/10.1111/acel.13648 |
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