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Nicotinamide riboside and caffeine partially restore diminished NAD availability but not altered energy metabolism in Alzheimer's disease

The redox co‐factor nicotinamide adenine dinucleotide (NAD) declines with age, and NAD deficits are specifically associated with dysfunctional energy metabolism in late‐onset Alzheimer's disease (LOAD). Nicotinamide riboside (NR), a dietary NAD precursor, has been suggested to ameliorate the ag...

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Detalles Bibliográficos
Autores principales: Ryu, Woo‐In, Shen, Minqi, Lee, Yoon, Healy, Ryan A., Bormann, Mariana K., Cohen, Bruce M., Sonntag, Kai‐Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282847/
https://www.ncbi.nlm.nih.gov/pubmed/35730144
http://dx.doi.org/10.1111/acel.13658