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Modelling the response to vaccine in non-human primates to define SARS-CoV-2 mechanistic correlates of protection

The definition of correlates of protection is critical for the development of next-generation SARS-CoV-2 vaccine platforms. Here, we propose a model-based approach for identifying mechanistic correlates of protection based on mathematical modelling of viral dynamics and data mining of immunological...

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Detalles Bibliográficos
Autores principales: Alexandre, Marie, Marlin, Romain, Prague, Mélanie, Coleon, Severin, Kahlaoui, Nidhal, Cardinaud, Sylvain, Naninck, Thibaut, Delache, Benoit, Surenaud, Mathieu, Galhaut, Mathilde, Dereuddre-Bosquet, Nathalie, Cavarelli, Mariangela, Maisonnasse, Pauline, Centlivre, Mireille, Lacabaratz, Christine, Wiedemann, Aurelie, Zurawski, Sandra, Zurawski, Gerard, Schwartz, Olivier, Sanders, Rogier W, Le Grand, Roger, Levy, Yves, Thiébaut, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282856/
https://www.ncbi.nlm.nih.gov/pubmed/35801637
http://dx.doi.org/10.7554/eLife.75427